What are methods of therapeutic drug monitoring?
Abstract. The availability of new immunoassay and chromatographic methods has led to the revolution in therapeutic drug monitoring. The immunochemical and chromatographic methods both meet the analytical requirements of sensitivity, precision, and accuracy needed for most TDM applications.
What does therapeutic test mean?
Definition of therapeutic test : a test to aid in diagnosis of an undiagnosed disease by giving the specific remedy for the disease suspected use of liver extract as a therapeutic test for suspected pernicious anemia.
What does it mean if a drug is therapeutic?
Therapeutic: Relating to therapeutics, the branch of medicine that is concerned specifically with the treatment of disease. The therapeutic dose of a drug is the amount needed to treat a disease.
What is the importance of TDM?
What is the Importance of Therapeutic Drug Monitoring? Therapeutic drug monitoring helps in designing patient-specific dosage regimen; it aids in enhancing the efficacy of drugs, to reduce the toxicity of drugs and for diagnostic purposes, by individualizing drug therapy.
What are therapeutic drugs used for?
The purpose of using drugs is to relieve symptoms, treat infection, reduce the risk of future disease, and destroy selected cells such as in the chemotherapeutic treatment of cancer.
When is therapeutic drug monitoring done?
Therapeutic drug monitoring should be performed when the patient has achieved steady-state concentration, has changed drug therapy, or has had a change in response to treatment (eg, toxicity).
What are therapeutic drugs and examples?
What is it used for?
| Types of Medicine | Medicine Names |
|---|---|
| Heart drugs | digoxin, procainamide, lidocaine |
| Anti-seizure drugs | phenytoin, phenobarbital |
| Drugs treat autoimmune diseases | cyclosporine, tacrolimus |
| Drugs that treat bipolar disorder | lithium, valproic acid |
What are examples of therapeutic procedures?
Therapeutic Procedures and Exercises
- Mechanical Traction.
- Manual Therapeutics.
- Therapeutic Massage, Myofascial and Connective Tissue Release Techniques.
- Canalith Repositioning Procedures [CRP]
- Postural Training.
- Body Mechanics/Ergonomics.
- Neuromuscular Re-education.
- Gait Training.
What is TDM in pharmacology?
Therapeutic drug monitoring (TDM) is testing that measures the amount of certain medicines in your blood. It is done to make sure the amount of medicine you are taking is both safe and effective. Most medicines can be dosed correctly without special testing.
Which drug is suitable for TDM?
Therapeutic drug monitoring
| Drug | Therapeutic range (mg/L) |
|---|---|
| Phenobarbitone | 15 – 40 |
| Gentamicin, tobramycin, netilmicin | trough <2; peak >5 |
| Amikacin | trough <5; peak >15 |
| Vancomycin | trough <10; peak 20 – 40 |
What are therapeutics examples?
More specific measures that are employed to treat specific symptoms include the use of drugs to relieve pain or treat infection, surgery to remove diseased tissue or replace poorly functioning or nonfunctioning organs with fully operating ones, and counseling or psychotherapy to relieve emotional distress.
What is an example of a therapeutic drug?
Examples of drugs widely analysed for therapeutic drug monitoring: Aminoglycoside antibiotics (gentamicin) Antiepileptics (such as carbamazepine, phenytoin and valproic acid) Mood stabilisers, especially lithium citrate.