What is the theca folliculi?
Medical Definition of theca folliculi : the outer covering of a graafian follicle that is made up of the theca externa and theca interna.
Where do theca cells originate?
Theca cells originate from progenitor cells within the ovary and an adjacent fetal structure, the mesonephros. The ovary consists of a variety of cell types, each with distinct cellular origins. Granulosa cells, which surround the growing oocyte, originate with the epithelium that encases the ovary.
What is theca in Oogenesis?
The theca externa is the outer layer of cells comprised predominantly of nonsteroidogenic fibroblast-like cells that become part of a collagenous connective tissue. From: Encyclopedia of Reproduction (Second Edition), 2018.
What is theca lutea?
After rupture of the mature ovarian follicle, the theca interna cells differentiate into the theca lutein cells of the corpus luteum. Theca lutein cells secrete androgens and progesterone. Theca lutein cells are also known as small luteal cells.
What do granulosa cells secrete?
Granulosa cells are inside your ovaries. These cells produce estrogen, progesterone and other hormones. The hormones play a large part in the female reproductive system, from menstruation to ovulation to egg implantation.
What do theca interna cells secrete?
Theca interna cells are responsible for producing the C19 steroids that diffuse into the neighboring granulosa cells and serve as substrates for estrogen production.
How theca cells are formed?
Theca cells form in the secondary follicles, maintaining follicular structural integrity and secreting steroid hormones. Two main sources of theca cells exist: Wilms tumor 1 positive (Wt1+) cells native to the ovary and Gli1+ mesenchymal cells migrated from the mesonephros.
What does theca interna produce?
Is theca and lobe same?
Lobe is the flat part projecting from one of the ends of the anther filament. Anther is bilobed i.e it contains two lobes. Each lobe have two theca. Theca are the cavity in the lobes.
Is androgen a progesterone?
Progesterone is an anti-androgen because it competes with androgens for androgen receptors and an anti-estrogen because it downregulates estrogen receptors (Johnson and Everitt, 1995).
What is the function of theca?
Theca cells function in a diverse range of necessary roles during folliculogenesis; to synthesize androgens, provide crosstalk with granulosa cells and oocytes during development, and provide structural support of the growing follicle as it progresses through the developmental stages to produce a mature and …
What do granulosa cells and theca cells secrete?
The thecal cells secrete androgen and the granulosa cells secrete estrogen. The theca cells are found in the secondary follicles of the ovaries while the granulosa cells appear in the primary follicle and will secrete estrogen in response to follicle-stimulating hormone (FSH).